Shakib Al Hasan and Mohammad Saifuddin lead bowling honours as Australia routed yet again.
Mitch Swepson claims three wickets in his first appearance on the tour helps Australia beat Bangladesh at the fourth attempt.
The victory has helped them gain a 3-0 lead in the five-match series and registered their first series win over the visitors across formats.
Mustafizur Rahman had earlier played a key role in keeping Australia to just 121 for 7.
On a tough pitch to bat on, the visitors slipped to a 23-run defeat chasing a modest 132 for victory.
After keeper-batsman Mushfiqur Rahim and opener Tamim Iqbal, batsman Liton Das has been ruled out of the upcoming T20I series against Australia.
Australia to tour Bangladesh for five T20Is in August, 20-member squad announced.
Warner, Cummins and Maxwell among six to opt out of West Indies and Bangladesh tours.