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England 193 for 6 (Moeen 63, Roy 52, Holder 3-44) beat West Indies 159 for 5 (Mayers 40, Moeen 2-28) by 34 runs
Barbados: Moeen Ali produced a remarkable all-round display to lead England to victory in the fourth Twenty20 in Barbados on Saturday.
Stand-in captain Moeen struck a brutal 63 from 28 balls as England posted an imposing 193-6.
The all-rounder then took 2-28 in West Indies' reply as the hosts fell 34 runs short.
The series is perfectly poised at 2-2, with the final game to be played at the same venue on Sunday (20:00 GMT).
Having lost the toss, England started steadily on a slow pitch before Jason Roy capitalised on some loose West Indies bowling.
Roy hit three sixes in his 52, a fine effort from the opener despite looking out of sorts for much of his innings.
The bowling of Jason Holder and Kieron Pollard troubled England's batters with nagging consistency before Moeen's onslaught propelled England to their match-winning total.
There were cameos from Kyle Mayers, Nicholas Pooran and Holder in West Indies' reply but in contrast to England, none were able to post a significant score.
Roy's 34-ball fifty at the top of the order set a platform from which his team-mates could accelerate, James Vince chipped in with another elegant knock of 34 and Sam Billings hit two sixes from the last two balls to boost the tourists' total further.
But the magnificence of Moeen stole the show from them all.
The stylish left-hander was a joy to watch, the highlight being four consecutive sixes from Jason Holder's third over - whose figures read 1-3 before the England all-rounder intervened.
England hammered 15 sixes in total and Moeen accounted for seven of them.
He was assisted by some inconsistent West Indies bowling - full deliveries sailed back over their heads, shorter ones were pulled ferociously into the stands.
But the fact that he was batting on a pitch that looked two-paced and offering some uneven bounce made his effort even more impressive.
And as if a match-winning contribution with the bat wasn't enough, Moeen then went on to remove both West Indies openers with his off-spin, breaking a blistering opening stand of 64 from Mayers and Brandon King.
