Hardik and Chawla took three wickets each to help restrict Sunrisers Hyderabad to 173 before Suryakumar and Tilak sealed the chase.
The loss, by a huge 98-run margin, has pushed LSG out of the top four with the playoffs not far away.
Towhid, Mahmudullah unbeaten stand propels Bangladesh to 6-wicket win over Zimbabwe.
Fiery spells from Jadeja, Deshpande help Chennai beat Punjab by 28 runs.
RCB lost six wickets for only 25 runs in the chase after a strong start, but Karthik and Swapnil counterpunched to complete the win.
Shamar Joseph, Andre Russell included for home team in the global event.
South Africa men will take on Sri Lanka in two Tests and Pakistan in an all-format tour.
Cummins bowled a superb 19th over followed by Bhuvneshwar successfully defending 12 in the final over.
Meanwhile, star Men in Green pacer Haris Rauf returned to the squad after missing the recently concluded New Zealand series due to a shoulder injury
The spinners combined for eight boundary-less overs that fetched them four wickets for just 33 runs.