England 160 for 4 (Hales 53, Brook 42*, Usman Qadir 2-36) beat Pakistan 158 for 7 (Rizwan 68, Babar 31, Wood 3-24) by six wickets
Karachi: The returning Alex Hales hit 53 and debutant Luke Wood took 3-24 as England claimed a six-wicket Twenty20 win over Pakistan in their first game in the country for 17 years.
Chasing 159 to win the first T20, Hales hit seven fours in a controlled and mature knock in his first England appearance since 2019, when he was dropped from the World Cup squad for off-field issues.
His fifty gave England a platform for victory, with Harry Brook making 45 off 25 balls in just his fifth T20 to guide the tourists home with four balls to spare.
Earlier Pakistan made 158-7, with Mohammad Rizwan striking 68 from 46 balls, while opening partner and captain Babar Azam added 31 off 24.
Wood was supported by Adil Rashid, who took 2-27, including the key wicket of Babar with a brilliant googly to end an 85-run opening stand.
The match was England's first in the country for 6,118 days, since a Test and one-day international tour in December 2005.
No countries toured Pakistan between 2009 and 2015 after an attack by gunmen on the Sri Lanka team bus in 2009, with sides returning sporadically since then.
England were due to tour last winter, but withdrew after New Zealand's men abandoned their tour of Pakistan because of a security threat.
The second game in the seven-match series, which is a build-up to the T20 World Cup in Australia in October and November, is on Thursday.